Frequently asked questions

• How much weight can you lose using Wegovy®?

  Wegovy® is a highly effective treatment for weight management when used alongside a reduced calorie diet and increased physical activity.

   In clinical trials, participants lost an average of 14.9% of their body weight over approximately 15 months (68 weeks). Nearly one-third of people lost 20% or more of their body weight compared to those using lifestyle changes alone, who lost just 2.4%.

  Some people begin to feel reduced hunger within days, but meaningful weight loss typically occurs gradually. In the first month, participants in trials lost about 2% of their body weight, with steady progress continuing over time.

  To achieve the best results, Wegovy® should be combined with:

  • A balanced, reduced-calorie diet
    
    
  • Regular physical activity
    
    
  • Consistent weekly dosing as prescribed
    
    

  Your treatment will begin at a low dose and increase gradually to reduce side effects. Wegovy® is designed for long-term use, and your prescriber will work with you to monitor progress, adjust your care if needed, and guide any decisions about continuing or tapering off the medication.

• What BMI do I need to be to start treatment?

  You can start Wegovy or Mounjaro if you are an adult living with obesity, which means your BMI is 30 or higher.

  If your BMI is over 27 and you have health problems related to your weight, such as prediabetes, high blood pressure, sleep apnea, high cholesterol, or heart disease, you may also be eligible for treatment.

  If you are from an Asian, Black African, African-Caribbean, or Middle Eastern background, the BMI thresholds are lowered by 2.5, because people from these groups can have health risks at lower BMIs.

• Can I switch between Wegovy® and Mounjaro®?

  If you are currently using an injectable weight loss treatment and have not yet reached a weight loss plateau, we recommend staying on the same type of treatment. Continuing with your current medication allows your body to benefit from the treatment and helps maintain a consistent weight loss journey.

  However, if you wish to switch to a different injectable weight loss treatment, it is important to start from the lowest dose of the new medication, regardless of your previous treatment or dose. For example, if you were previously prescribed Wegovy (at any dose) and would like to switch to Mounjaro, you should always begin with the lowest available dose of Mounjaro, which is 2.5 mg.

  When switching between different types of injectable weight loss treatments, no "wash out" period is necessary.

  A "wash out" period refers to a time during which you would stop all medications to allow your body to clear out the previous treatment before starting a new one. 

  For example, if you were previously taking Wegovy 1.7mg and decided to switch to Mounjaro, you would not need to take a break between treatments. Instead, you can take your last dose of Wegovy 1.7mg as scheduled, and then start Mounjaro 2.5mg the following week, as per the recommended dosing schedule for Mounjaro.

• What’s the difference between Wegovy® and Mounjaro®?

  Wegovy® and Mounjaro® are both weekly injectable medicines used to support weight loss, but they work in slightly different ways.

  Wegovy® contains semaglutide, which mimics one gut hormone called GLP-1. This helps reduce appetite, slow digestion, and makes you feel fuller for longer.

  Mounjaro® contains tirzepatide, which mimics two hormones, GLP-1 and GIP. This dual action is thought to have a stronger effect on appetite regulation, cravings, and blood sugar control.

  In clinical trials, Mounjaro® has shown a higher average weight loss than Wegovy®. But everyone responds differently, and what works best for one person might not be right for another.

  If you're unsure which option is better for you, our clinical team can help you find the treatment that best suits your needs and goals

• How can I be 100% sure MedExpress is legal?

  We understand how important it is to feel confident in the safety and legitimacy of an online pharmacy. 

  MedExpress is a fully legal and regulated online pharmacy, and several layers of oversight ensure we meet the highest standards. 

  Our prescribing service is run by the Central Medical Solutions Ltd (CMS), a clinically led organisation regulated by the Care Quality Commission (CQC). MedExpress itself operates as the registered pharmacy responsible for dispensing and dispatching medications, and is regulated by the General Pharmaceutical Council (GPhC). For some prescriptions, we also work with Health Finder Pro, a trusted third-party provider that is also CQC-registered. 

  You can verify our credentials at any time:

  • We’re listed on the official GPhC online register
  • Our CQC registration can be found here
  • We are LegitScript verified (a global standard for safe and legitimate online healthcare)
  • We are also a member of the DiCE Network, which promotes digital clinical excellence

  All medications are dispensed from our licensed UK pharmacy by qualified healthcare professionals. 

  

  If you ever have any questions about how we work or want to check anything for yourself, our team is here to help.

• Do I need a prescription to order?

  No, you don’t need an existing prescription to order with MedExpress. 

  When you place an order, you will complete a free online consultation form. This allows our UK-registered prescribers to assess whether the treatment is safe and appropriate for you. Here’s how it works:

  1. Complete the online consultation for your desired treatment
  2. Pay for your medication (including any delivery charges)
  3. Your consultation is reviewed by one of our licensed prescribers
  4. If you are approved, we issue a private prescription and dispatch your medication
  5. If you are not eligible, we will let you know and issue a full refund.

  If you have any questions about this process, please contact us here.

• Can I use an existing prescription?

  We are not able to dispense medication using an existing NHS or private prescription.
  

  However, if you have used a treatment before, you can let us know during your online consultation. It may help our clinical team assess your suitability more quickly. 
  
  

  To ensure your safety, one of our UK-registered prescribers must issue a new private prescription before the medication is supplied.
  
  We offer a free online consultation process, and you will only pay for treatment if you are eligible and decide to go ahead with the treatment.
  
  

  If you have any questions about how this works, please contact us here.

• What is your return and refund policy?

  For safety reasons, we cannot accept returns of medicines once they have been prescribed and dispensed. This is because medication cannot legally be reused or reissued once it has left the pharmacy, even if unopened.
  
  

  If you have any unwanted medication, we recommend taking it to your local pharmacy for safe disposal.
  
  

  Can I still cancel my order?

  Yes, you may cancel your order at any time before it has been prescribed by our clinical team.
  Once a prescription has been issued, we’re no longer able to cancel or refund the order.
  
  

  If your cancellation request is accepted, your refund will be issued as account credit, which can be used for future purchases and does not expire.
  
  

  To request a cancellation, please reach out to our Customer Care team using our Contact Form.

• Is the service confidential?

  Yes, your privacy is extremely important to us.
  
  

  At MedExpress, your medical information and order history are completely confidential. Only our registered pharmacy team and prescribers have access to this data, and we never share your information with third parties.
  
  

  Once your order is placed, your account becomes anonymised and handled securely in line with our Privacy Policy.
  
  

  You also have full control over how discreet your experience is:

  • What appears on your bank statement (your transaction will show as MEXPRESS).

  • Where your parcel is delivered — to your home, or to a nearby Post Office™ for collection.

   

   

   

• Is the packaging discreet?

  Yes, all of our packaging is completely plain and unbranded.
  
  

  Orders are sent in plain brown padded envelopes or boxes, with no logos, pharmacy names, or branding of any kind. The only visible marking is your address label on the front of the parcel.
  
  

  There’s no mention of MedExpress or what’s inside the package.
  
  

  If you’d prefer not to receive your parcel at home, you can also choose delivery to a local Post Office™ for added privacy.

   

   

• Will my GP be informed of my treatment?

  It depends on the treatment you are receiving.

  For certain medications, we do require your consent to inform your GP. This is the case for:

  • GLP-1 medications for weight management
  • Orlistat for weight management
  • Ventolin for asthma

  This is to ensure safe prescribing and proper ongoing care. If you don’t consent to us informing your GP, we won’t be able to complete your consultation or supply the treatment. 

  For most other treatments, informing your GP is optional and won’t affect your ability to receive treatment. You will be given the choice during the online consultation.

  If you are unsure or have any questions, please contact us here.