No. Wegovy® (semaglutide) has not been shown to make hormonal contraception, such as the birth control pill, less effective. Clinical studies have found that taking semaglutide does not meaningfully change the levels of contraceptive hormones in your body.

Use this guide to understand:

Research indicates that Wegovy® does not interfere with how your contraceptive pill works biologically. The hormones in your birth control should remain at effective levels in your system while you are using this weight loss treatment.

While the medication doesn't block the pill, certain side effects can indirectly affect how well your body absorbs oral medication. Much like a stomach bug, if you experience the following, your contraception may be compromised:

In these instances, you should follow the "missed pill" guidance provided with your specific contraceptive brand or use a backup method (such as condoms) until you are well again.

If you are planning to become pregnant, you should stop taking Wegovy® at least two months before trying to conceive. Please speak with your GP or a healthcare professional to discuss your transition off the medication safely.

It is important to continue using reliable contraception while on Wegovy® if you do not plan to become pregnant. While Wegovy® itself is safe to use alongside the pill, staying mindful of how your body reacts to the treatment ensures you remain fully protected. If you experience persistent digestive side effects, you may want to discuss alternative, non-oral contraceptive methods (such as the implant or coil) with your GP, as these are not affected by digestive upset.

If you still need help after reviewing the information above, additional assistance is available from the MedExpress team.