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How do I manage heart palpitations or an increased heart rate while taking Mounjaro or Wegovy?

Overview

Heart palpitations are a possible side effect of Wegovy® and Mounjaro®. This article explains how this symptom may feel, practical steps to help manage it, and when to seek medical support. Use this information if you notice a racing or unusually strong heartbeat while taking either medication.

Use this article when you want to:

  • Understand why heart palpitations can happen with Wegovy® or Mounjaro®.

  • Find practical steps to help monitor and manage palpitations.

  • Know when to contact your GP, call 111, or call 999.


Why Can Heart Palpitations Happen With Wegovy® or Mounjaro®?

Heart palpitations are an uncommon side effect of Wegovy® and Mounjaro®, affecting fewer than 1 in 100 people.

An increased heart rate may feel like:

  • A fast pulse.

  • A racing or pounding heartbeat, even while resting.

  • An increased awareness of your heartbeat (palpitations).

Researchers are still studying why some people experience an increased heart rate while taking weight loss medication such as Wegovy® or Mounjaro®.


What Can Help Manage Heart Palpitations?

If symptoms are mild, the following steps may help you monitor and reduce palpitations.

Monitor Your Heart Rate

  • Keep track of your resting heart rate, either manually or with a smartwatch or fitness tracker.

  • Make a note of:

    • When palpitations occur.

    • How long they last.

    • Whether they happen at rest or after certain activities.

This information can be helpful if you need to speak with a clinician.

Reduce Common Triggers

Certain substances can raise your heart rate and make palpitations more noticeable. Consider reducing or avoiding:

  • Caffeine

  • Alcohol

  • Smoking or nicotine products


When Should I Contact My GP or Call 111?

Contact your GP or call 111 if:

  • You experience repeated palpitations that keep coming back or worsen over time.

  • You have a family history of heart problems.

When seeking medical advice, make sure you tell your healthcare provider that you are taking weight loss medication, including Wegovy® or Mounjaro®.


When Should I Contact 999?

Contact 999 immediately if heart palpitations are accompanied by any heart attack symptoms, such as chest pain, or tightness in the chest, neck, jaw, arm, or back — this can be a sign of a cardiac event.


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