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How do I manage fatigue and tiredness while taking Mounjaro or Wegovy?

Overview

Use this article to understand why you might feel tired while taking Mounjaro® or Wegovy®, and to find nutrition and lifestyle habits that can help manage fatigue.

Use this article when you want to:

  • Understand why you might feel tired during your weight loss journey with Mounjaro® or Wegovy®

  • Identify key nutrients that support energy production

  • Learn lifestyle habits that can improve your sleep and energy levels


Why Does Fatigue Happen While Taking Mounjaro® or Wegovy®?

Fatigue is a very common side effect of Wegovy®, affecting more than 1 in 10 people. It is also a common side effect of Mounjaro®, occurring in up to 1 in 10 people.


Nutritional Support for Energy

When taking Mounjaro® or Wegovy®, your appetite is reduced. It's essential to ensure that the food you do eat provides the energy your body needs:

  • Calorie intake: Ensure you are eating enough nutrient-dense food to meet your daily energy requirements.

  • Vitamin B12: This vitamin is crucial for energy production. It's naturally found in meat, fish, cheese, and eggs.

  • Vitamin D: Low levels of vitamin D are linked to fatigue. Your body produces vitamin D from sunlight exposure, and it's also found in oily fish, red meat, liver, and egg yolks — speak to your GP if you're concerned about your sun exposure or whether a supplement might help.

  • Iron: Low iron levels are a common cause of tiredness. To boost your iron intake, eat foods such as liver, red meat, and beans (including red kidney beans, edamame, and chickpeas).


Lifestyle Habits to Combat Fatigue

Adjusting your daily routine can significantly reduce the impact of fatigue while taking Mounjaro® or Wegovy®:

  • Regular exercise: While it may seem counterintuitive when tired, regular physical activity can actually boost your long-term energy levels.

  • Consistent sleep schedule: Try to go to bed and wake up at the same time every day. Aim for 7 to 9 hours of sleep per night.

  • Optimise your sleep environment: Ensure your bedroom is relaxing by keeping it dark, quiet, and at a cool temperature.


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