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Managing a gap in treatment for Mounjaro or Wegovy

Overview

A gap in treatment is the length of time between your last Mounjaro® or Wegovy® prescription date and the date you place a new order. When you resume or restart Mounjaro® or Wegovy® treatment, MedExpress always calculates this gap to ensure your next dose is safe and appropriate for your current needs.

Use this article when you want to:

  • Understand how the length of your break from Mounjaro® or Wegovy® affects your next dose

  • Find out your options for continuing or restarting treatment

  • Understand how dose amendments are handled after a treatment gap


How Does My Treatment Gap Affect My Next Mounjaro® or Wegovy® Dose?

The duration of your break from Mounjaro® or Wegovy® determines the clinical options available for your next order.

Gap of Less Than 8 Weeks

If your break is shorter than 8 weeks, you typically have two options:

  • Stay on your previous dose: if your last dose worked well and side effects were manageable, you can continue at that same strength.

  • Move up to the next dose: if you tolerated your previous dose well and wish to continue your weight loss progress, you can move up following the standard Mounjaro® or Wegovy® titration schedule.

Gap of Between 8 and 12 Weeks

A clinical review will determine the safest path forward, which may include:

  • Continuing with your previous Mounjaro® or Wegovy® dose.

  • Stepping down to a lower dose to allow your body to readjust to the medication.

Gap of Between 12 Weeks and 6 Months

Because your body's sensitivity to Mounjaro® or Wegovy® changes over time, MedExpress's clinical team will decide whether you should:

  • Continue with your previous dose.

  • Step down to a lower dose.

  • Restart treatment from the initial starting dose.

Gap of More Than 6 Months

If it's been over 6 months since your last treatment with MedExpress, you must restart your Mounjaro® or Wegovy® journey at the lowest available dose, to minimise the risk of severe side effects.


What Else Do I Need to Know?

  • Safety first: all dosing decisions are made with your safety as the highest priority. The guidance above assumes your last dose was well-tolerated. If you previously experienced significant side effects, a lower dose may be recommended regardless of the gap length.

  • Clinical discretion: decisions regarding the appropriate dose are final. If MedExpress's clinical team determines a different dose is required for your safety, you'll have the following options:

    1. Agree to have your order dose amended as directed.

    2. Have your order cancelled and receive a full refund.


Where Can I Find More Guidance on My Weight Loss Journey?

For further guidance on managing your wider weight loss journey with Mounjaro® or Wegovy®, visit MedExpress's dedicated GLP-1 Hub.

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