Managing persistent side effects on Mounjaro

If you're experiencing persistent side effects on Mounjaro®, such as nausea, vomiting, or diarrhoea, this is often temporary while your body adjusts to the medication. Digestive symptoms are common during dose increases and usually improve over time. This guide explains practical ways to manage Mounjaro® side effects, when a dose adjustment may be considered, and when further clinical review may be needed.

Use this article when you want to:

To help manage Mounjaro® side effects while your body adapts, MedExpress recommends the following:

Eat smaller meals more frequently throughout the day rather than three large meals. Smaller portions are often easier to tolerate when using Mounjaro®.

Drink plenty of fluids throughout the day, especially if you are experiencing vomiting or diarrhoea. Good hydration helps reduce the risk of dehydration while taking Mounjaro®.

Try to avoid greasy, rich, or highly processed foods, as these can worsen nausea. Simple, bland meals are often better tolerated during the early stages of Mounjaro® treatment.

If persistent side effects on Mounjaro® do not improve or begin to interfere with daily life, your treatment plan may need review. Depending on your circumstances, your MedExpress prescriber may consider:

Any dose changes are based on clinical assessment and tolerability.

Further review may be appropriate if: