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How do I choose the right GLP-1 strength?

Overview

Choosing the right strength for a GLP-1 medication such as Mounjaro® or Wegovy® is based on safe clinical dosing guidelines, not guesswork. Your MedExpress prescriber sets your starting dose and any later dose increases according to your individual tolerance and progress.

Use this article when you want to:

  • Understand how your starting dose of Mounjaro® or Wegovy® is chosen

  • Find out how Mounjaro® or Wegovy® dose increases usually work

  • Understand why the right strength depends on safety and tolerance, not on reaching the highest dose


What Starting Dose Do I Begin GLP-1 Treatment At?

All patients begin GLP-1 treatment, such as Mounjaro® or Wegovy®, at the lowest starting dose.

Starting at the lowest dose helps:

  • Reduce the chance of side effects

  • Allow your body time to adjust safely

  • Support steady, sustainable weight loss


How Does My Mounjaro® or Wegovy® Dose Increase Over Time?

If your current Mounjaro® or Wegovy® dose is well tolerated, your MedExpress prescriber may increase your strength gradually, usually every 4 weeks.

Dose increases are based on:

  • Your side-effect tolerance

  • Your weight-loss progress

  • Your overall clinical safety


Do I Need to Reach the Highest Dose?

Not everyone needs the highest available dose of Mounjaro® or Wegovy®. Many patients stay on a lower maintenance strength that works well for them, with manageable side effects and steady results.

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